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Research Associate/Senior Research Associate, Molecular and Cellular Biology

Who we are:

Calico is a research and development company whose mission is to harness advanced technologies to increase our understanding of the biology that controls lifespan. We will use that knowledge to devise interventions that enable people to lead longer and healthier lives. Executing on this mission will require an unprecedented level of interdisciplinary effort and a long-term focus for which funding is already in place.

Position description:

Calico is inviting applications from biologists who are excited to work within a scientific team with a translational drug development focus. The RA/SRA will fill a hands-on bench position and be responsible for a variety of experiments, ranging from established molecular biology to novel assay development and optimization. The successful candidate will be detail-oriented, organized, flexible and self-motivated. He/she will support projects within the lab but will also be expected to design, plan and execute studies under the supervision of the PI.

Position requirements:

  • BS/MS with minimum 3 years of technical experience, or a PhD in cell biology, biochemistry or a related discipline
  • Experience with standard molecular cloning techniques (PCR, Gibson assembly, DNA/RNA prep) and mammalian cell culture
  • Experience with standard protein biochemistry techniques (preparation of cell-lysates, SDS-PAGE, Western Blot, microplate-based assays)
  • Experience with live cell (time-lapse) and fixed (immunofluorescence) microscopy
  • Must be a good team player, capable of working on multiple projects, and have strong communication skills

Preferred skills:

  • Experience with CRISPR (knockouts, knock-ins) and culturing of primary cells/IPSCs is a strong plus
  • Experience with mouse work (tissue harvesting, sectioning, histology) is a strong plus
  • Experience with more advanced microscopy techniques (IHC, FRET, TIRF, single-molecule FISH, image quantitation) is a plus
  • Experience with R or Python is a plus
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